Recombinant IL-5 antibody (AA 20-134)

Catalog No. ABIN7795773

The Rabbit Monoclonal anti-IL-5 antibody has been validated for WB. It is suitable to detect IL-5 in samples from Human.

Quick Overview for Recombinant IL-5 antibody (AA 20-134) (ABIN7795773)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL-5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: BLR343M

Product Details anti-IL-5 Antibody

Binding Specificity: AA 20-134

Purpose: Rabbit anti-IL-5 Recombinant Monoclonal Antibody [BLR343M]

Purification: Purified

Immunogen: residues 20-134

Isotype: IgG

Application Details

Application Notes: WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: IL-5

Background: IL-5 is a homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. IL-5 also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. IL-5 exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P05113].

Gene ID: 3567

UniProt: P05113

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour